Ebola vaccine trials raise ethical issues
نویسندگان
چکیده
منابع مشابه
Ethical issues in tuberculosis vaccine trials.
Bacille Calmette-Guérin (BCG) vaccines are widely used, even though estimates of efficacy have ranged from zero to 80%. BCG is a relatively safe vaccine, but it can cause disseminated infection, especially in immunocompromised hosts. Thus, the development of a more reliably efficacious and safer vaccine is important to the control of tuberculosis. The testing of any new vaccine in human populat...
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1Center for Computational Biology and Bioinformatics, The University of Texas at Austin, Austin, TX 78712, USA; 2Department of Biology and Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA; 3Department of Biology and Institute of Infectious Disease Research, McMaster University, Hamilton, ON, Canada; 4Department of Integrative Biology, The University of Texas at Austin, ...
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1134 www.thelancet.com/infection Vol 15 October 2015 would be confounded with other factors associated with infection risk. The relative merits of trial designs are context-specifi c, and the benefi ts conventionally associated with certain designs might be achieved by alternative designs, when carefully tailored to local situations. We believe that proposed designs should be rigorously analyse...
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ژورنال
عنوان ژورنال: Science
سال: 2014
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.346.6207.289